Research Interest:ÌýComputational Chemistry: Modeling studies of bioinorganic systems, including thyroid activation and oxidative scavenging.
Research Interest: Biochemistry; Bioinformatics: The fundamental determinants of protein structure, stability, folding and evolution are investigated as well as genomic adaption.
Research Interest:ÌýBioinorganic Chemistry:ÌýTransition metal complexes as inorganic pharmaceuticals.
Research Interest: Bioenergetics: Exploration of the role of protons and water in the mitochiondia are undertaken to address their functional role in proton coupling energy transduction and implications in human health and aging.
Research Interest:ÌýGenetics: Nanotoxicology, identifying cellular responses to nanomaterials in epigenetics, mutagenesis, and immunotoxicity.
Research Interest: Structural Biology; Virology: Development and Application of Structural Biology approaches to medically relevant systems, such as virus replication machinery, and proteins linked to cancer and Alzheimer's disease.
Research Interest:ÌýComputational Chemistry: Molecular dynamics simulations are performed on proteins to study their folding.
Dr. Erin Purcell Biochemistry; Signal Transduction: The role of intracellular signaling pathways in bacterial pathogenesis is studied to guide the design of enzyme inhibitors that could serve as novel antibiotics.
Dr. Bala Ramjee Nanomaterials: A major focus is on the synthesis and functionalization of nanocapsules for drug delivery and in vivo imaging. Another area is functionalization and sensing using inorganic nanoparticles.
Dr. Guijun Wang Drug Synthesis; Chemical Biology: We are interested in the synthesis and properties of compounds of biological activities. These include chiral small molecules that are building blocks for many drugs and certain enzyme inhibitors that are important for cardiovascular systems. Another main area of focus is to synthesize and study soft biomaterials.
Dr. Nancy Xu BRAIN/Single Cell/Cancer Biology/Nanobiotechnology/Nanomedicine/Nanotoxicity/ Optogenetics: Modern Molecular Biomedical Sciences/Engineering: The Xu lab has been developing cutting-edge technologies, including Single Molecular and Single Live Cell Imaging, Single-Cell Genomics, Nanobiotechnology, and Optogenetics, to unlock neuron-neuron communication, revolutionize early cancer detection, unravel developmental biology (embryonic stem cell differentiation), decipher nanotoxicity, understand multidrug resistance, and design groundbreaking nanomedicines and biocompatible nanomaterials.